Some of the software that you're running is great. I run Perfect Disk 11 myself. Perhaps the best paid defrag tool on the market. It does what the free ones cant do.
Avast Free, it's OK for web browsing (see the specs on their home site), but as far as banking, making transactions, etc, no. They offer a 3 user Pro pack for $29.99, which includes full protection. They also have a 3 star rating with AV Comparatives, meaning it's among the best in the industry. Had I not found the 3 Pack of ESET NOD32 AV 4 for $29.99 (thanks to the link that yodap provided), I would have chosen Avast Pro or Ad-Aware Pro. Both can be had for $29.99, but Ad-Aware is only a single user pack.
Advanced System Care (Pro or Free) concerns me. It (the free version) wiped out an XP install a couple of years ago. It's "cleaning" is too aggressive for my comfort level. That money would be better spent on a paid AV (see above). CCleaner does a good job of cleaning the junk files from your computer, plus it has a SAFE registry cleaner. It reminds you to backup the registry to your docs, as always, you should do so.
HijackThis, I have it, but haven't actually had to use it, and hope that I don't need to.
Spybot, I've ran it for a limited time, I had problems with the Tea Timer function on it. Other than that, I didn't run it enough to really say how good (or bad) it is, so I'll leave it at that.
If by chance you do keep Avast Free (I really recommend the paid version for it's extra security, I believe that a single user license is $19.99/year, if you don't need the 3 pack), you need to run that ESET Online Scanner weekly. Most of us do make purchases on the internet, it's more convenient to shop the net, rather than drive around, plus you can hunt for the best deal, while saving a ton in gas (which alone can pay for the pro version of Avast). And keep in mind, that "free" AV's leave out critical components that we need to stay safe at all times.
By running ESET weekly, you'll at least know that you have a fairly clean computer, but remember, it's not "realtime protection". I also feel that's a step that you should take, ASAP, to be sure that you don't have any viruses or other bad code that Avast Free may have missed.
I think that the bases have been covered, but I still feel that you need to disable some of the addons that you don't use daily. The more that the browser has to load at startup, the slower it will be. For example, when I start IE9 RC, it offers to disable addons to gain startup speed. And I only have 5 addons.
Hopefully, my post is of some help to you, it looks like you're doing some good things. I hope that you get your images running fast again. If you need further assistance, post back. There's usually help around somewhere, and I'll keep an eye out for you, too.
Cat