Installing programs on another drive

Is it possible to install programs on a drive other than your C drive? It seems Windows is getting a little sluggish and I'm wondering if it's because of all the programs I have loaded. I only have a couple that run on startup, and Windows is running pretty solid, but I think it's losing some of its snap, if you know what I mean.


Edit: Never mind...I found another thread dealing with the same subject. Thanks and please delete.

10-4...but for your computer sluggishness, have you checked your system for any malware, spyware, defragged your hard drive, clean out your registry from broken and/or missing strings. This will help your performance.

Yes to all of the above, and it's not really sluggish, it just doesn't have that new OS snap anymore...