As you can see I have two 500GB hard drives. After they're formatted the size is 465.76GB in size. Drive 0 is where I have my Windows 7 installed. You can see the 100MB MBR partition that Windows 7 automatically creates when installing the OS. I make my C drive a 64GB partition. The remainder of the hard drive is for miscellaneous stuff.
Here's a tip: To make a 64GB partition along with the 100MB MBR when installing Windows 7, make a partition size of 65,639 MB in size, then when Windows 7 makes the 100 MB MBR partition and the rest of the partition becomes a 64GB!
That may be bigger than what most recommend, but I like it that way. I have my Paging File on Drive 1, since I have learned that Windows likes the Paging File better when it's on a separate hard drive and a lot of experts recommend that type of setup.
I always change the drive letters to reflect that the CD/DVD drive is Drive D, since that has always been the traditional way of doing it by default. I suppose it really doesn't matter, but I guess I'm anal when it comes to that.